Botox vs Xeomin: What's the Difference?
Botox and Xeomin are two of the most requested treatments at KoraSkinMD — and patients often ask how they differ.
What Are Botox and Xeomin?
Both are neuromodulator treatments made with botulinum toxin type A. In aesthetics, they're used to temporarily relax specific facial muscles that contribute to expression lines — the lines that form from repeated movement over time, like frowning, squinting, smiling, or raising the brows.
In simple terms:
They help calm the muscle movement that creates certain lines
They do not add volume
They do not fill the skin
They do not change your bone structure
The American Academy of Dermatology explains that dermatologists use botulinum toxin therapy to diminish signs of aging, including frown lines and crow's feet. Cleveland Clinic similarly describes Botox as relaxing the muscles responsible for wrinkles.
The Actual Difference
Botox and Xeomin both use botulinum toxin type A — the difference is in formulation. Cleveland Clinic explains that Xeomin is a purified form of the toxin, while Botox contains additional proteins around the active ingredient. That's why Xeomin is sometimes called a "naked injectable."
For many patients, the experience and result feel very similar. The right choice depends on your treatment history, goals, facial movement, and your physician's clinical judgment — a decision made during consultation, not chosen off a menu.
What Areas Can Be Treated?
Frown Lines — the vertical "11 lines" between the brows that can make the face look tense even when you feel calm.
Forehead Lines — horizontal lines that appear when raising the brows; conservative treatment softens them without erasing natural expression.
Crow's Feet — fine lines at the outer corners of the eyes, often from smiling or squinting.
Brow Area — careful placement can create a more rested appearance.
Jawline and Masseter Area — for strong jaw muscles, treatment may relax the masseter to soften lower-face width and support facial balance.
Not every patient needs every area treated. The most natural results usually come from a physician recommending only what actually needs support.
Which One Is Right for You?
That's a physician-led decision, made after evaluating your facial movement, treatment history, and goals. Book a consultation with KoraSkinMD in San Francisco to find out whether Botox, Xeomin, or another approach fits you best.
